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Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration
BACKGROUND: Retinal degenerative diseases significantly contribute to visual impairment and blindness. Microglia reactivity is a hallmark of neurodegenerative diseases including retinal cell death and immunomodulation emerges as a therapeutic option. Indole-3-carbinol (I3C) is a natural ligand of ar...
Autores principales: | Khan, Amir Saeed, Langmann, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640677/ https://www.ncbi.nlm.nih.gov/pubmed/33143743 http://dx.doi.org/10.1186/s12974-020-01999-8 |
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