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A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger
BACKGROUND: Cutaneous fibrous histiocytoma (CFH) is a common, benign skin tumor predominantly occurring on the extremities or trunk. However, CFH on the finger is rare. OBJECTIVE: This study was undertaken to examine the clinicohistopathological features of CFH of the finger. MATERIALS AND METHODS:...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640793/ https://www.ncbi.nlm.nih.gov/pubmed/33165359 http://dx.doi.org/10.4103/ijd.IJD_366_18 |
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author | Nam, Kyung-Hwa Park, Sang-Woo Yun, Seok-Kweon |
author_facet | Nam, Kyung-Hwa Park, Sang-Woo Yun, Seok-Kweon |
author_sort | Nam, Kyung-Hwa |
collection | PubMed |
description | BACKGROUND: Cutaneous fibrous histiocytoma (CFH) is a common, benign skin tumor predominantly occurring on the extremities or trunk. However, CFH on the finger is rare. OBJECTIVE: This study was undertaken to examine the clinicohistopathological features of CFH of the finger. MATERIALS AND METHODS: This is a retrospective study of 12 CFHs located on fingers in a tertiary hospital in Korea. All case slides were retrieved from saved files. RESULTS: Ages of the CHF of the finger affected individuals ranged from 9 to 48 years with a male-to-female ratio of 1.4:1. Picker's nodule or wart was the most common clinical diagnosis. In only 2 out of the 12 cases was the pre-biopsy diagnosis of CFH ventured. Fibrocollagenous type was the most common histological type. Majority of the cases were mitotically inactive, exhibiting only 0–1 mitoses per high-power field and there was no recurrence. Tumor cells were uniformly CD34 negative. CONCLUSION: Because CFH can resemble malignancies including dermatofibrosarcoma protuberans, a lack of familiarity with the occurrence of CFH of the finger may lead to more aggressive treatment. Dermatologists should include CFH in their differential diagnosis of circumscribed nodules on the fingers to ensure proper management. |
format | Online Article Text |
id | pubmed-7640793 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-76407932020-11-05 A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger Nam, Kyung-Hwa Park, Sang-Woo Yun, Seok-Kweon Indian J Dermatol Short Communication BACKGROUND: Cutaneous fibrous histiocytoma (CFH) is a common, benign skin tumor predominantly occurring on the extremities or trunk. However, CFH on the finger is rare. OBJECTIVE: This study was undertaken to examine the clinicohistopathological features of CFH of the finger. MATERIALS AND METHODS: This is a retrospective study of 12 CFHs located on fingers in a tertiary hospital in Korea. All case slides were retrieved from saved files. RESULTS: Ages of the CHF of the finger affected individuals ranged from 9 to 48 years with a male-to-female ratio of 1.4:1. Picker's nodule or wart was the most common clinical diagnosis. In only 2 out of the 12 cases was the pre-biopsy diagnosis of CFH ventured. Fibrocollagenous type was the most common histological type. Majority of the cases were mitotically inactive, exhibiting only 0–1 mitoses per high-power field and there was no recurrence. Tumor cells were uniformly CD34 negative. CONCLUSION: Because CFH can resemble malignancies including dermatofibrosarcoma protuberans, a lack of familiarity with the occurrence of CFH of the finger may lead to more aggressive treatment. Dermatologists should include CFH in their differential diagnosis of circumscribed nodules on the fingers to ensure proper management. Wolters Kluwer - Medknow 2020 /pmc/articles/PMC7640793/ /pubmed/33165359 http://dx.doi.org/10.4103/ijd.IJD_366_18 Text en Copyright: © 2020 Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Short Communication Nam, Kyung-Hwa Park, Sang-Woo Yun, Seok-Kweon A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger |
title | A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger |
title_full | A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger |
title_fullStr | A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger |
title_full_unstemmed | A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger |
title_short | A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger |
title_sort | clinicohistopathological analysis of cutaneous fibrous histiocytomas of the finger |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640793/ https://www.ncbi.nlm.nih.gov/pubmed/33165359 http://dx.doi.org/10.4103/ijd.IJD_366_18 |
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