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A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger

BACKGROUND: Cutaneous fibrous histiocytoma (CFH) is a common, benign skin tumor predominantly occurring on the extremities or trunk. However, CFH on the finger is rare. OBJECTIVE: This study was undertaken to examine the clinicohistopathological features of CFH of the finger. MATERIALS AND METHODS:...

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Autores principales: Nam, Kyung-Hwa, Park, Sang-Woo, Yun, Seok-Kweon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640793/
https://www.ncbi.nlm.nih.gov/pubmed/33165359
http://dx.doi.org/10.4103/ijd.IJD_366_18
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author Nam, Kyung-Hwa
Park, Sang-Woo
Yun, Seok-Kweon
author_facet Nam, Kyung-Hwa
Park, Sang-Woo
Yun, Seok-Kweon
author_sort Nam, Kyung-Hwa
collection PubMed
description BACKGROUND: Cutaneous fibrous histiocytoma (CFH) is a common, benign skin tumor predominantly occurring on the extremities or trunk. However, CFH on the finger is rare. OBJECTIVE: This study was undertaken to examine the clinicohistopathological features of CFH of the finger. MATERIALS AND METHODS: This is a retrospective study of 12 CFHs located on fingers in a tertiary hospital in Korea. All case slides were retrieved from saved files. RESULTS: Ages of the CHF of the finger affected individuals ranged from 9 to 48 years with a male-to-female ratio of 1.4:1. Picker's nodule or wart was the most common clinical diagnosis. In only 2 out of the 12 cases was the pre-biopsy diagnosis of CFH ventured. Fibrocollagenous type was the most common histological type. Majority of the cases were mitotically inactive, exhibiting only 0–1 mitoses per high-power field and there was no recurrence. Tumor cells were uniformly CD34 negative. CONCLUSION: Because CFH can resemble malignancies including dermatofibrosarcoma protuberans, a lack of familiarity with the occurrence of CFH of the finger may lead to more aggressive treatment. Dermatologists should include CFH in their differential diagnosis of circumscribed nodules on the fingers to ensure proper management.
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spelling pubmed-76407932020-11-05 A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger Nam, Kyung-Hwa Park, Sang-Woo Yun, Seok-Kweon Indian J Dermatol Short Communication BACKGROUND: Cutaneous fibrous histiocytoma (CFH) is a common, benign skin tumor predominantly occurring on the extremities or trunk. However, CFH on the finger is rare. OBJECTIVE: This study was undertaken to examine the clinicohistopathological features of CFH of the finger. MATERIALS AND METHODS: This is a retrospective study of 12 CFHs located on fingers in a tertiary hospital in Korea. All case slides were retrieved from saved files. RESULTS: Ages of the CHF of the finger affected individuals ranged from 9 to 48 years with a male-to-female ratio of 1.4:1. Picker's nodule or wart was the most common clinical diagnosis. In only 2 out of the 12 cases was the pre-biopsy diagnosis of CFH ventured. Fibrocollagenous type was the most common histological type. Majority of the cases were mitotically inactive, exhibiting only 0–1 mitoses per high-power field and there was no recurrence. Tumor cells were uniformly CD34 negative. CONCLUSION: Because CFH can resemble malignancies including dermatofibrosarcoma protuberans, a lack of familiarity with the occurrence of CFH of the finger may lead to more aggressive treatment. Dermatologists should include CFH in their differential diagnosis of circumscribed nodules on the fingers to ensure proper management. Wolters Kluwer - Medknow 2020 /pmc/articles/PMC7640793/ /pubmed/33165359 http://dx.doi.org/10.4103/ijd.IJD_366_18 Text en Copyright: © 2020 Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Short Communication
Nam, Kyung-Hwa
Park, Sang-Woo
Yun, Seok-Kweon
A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger
title A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger
title_full A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger
title_fullStr A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger
title_full_unstemmed A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger
title_short A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger
title_sort clinicohistopathological analysis of cutaneous fibrous histiocytomas of the finger
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640793/
https://www.ncbi.nlm.nih.gov/pubmed/33165359
http://dx.doi.org/10.4103/ijd.IJD_366_18
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