Cargando…

Insights from nanotechnology in COVID-19 treatment

In just a few months, SARS-CoV-2 and the disease it causes, COVID-19, created a worldwide pandemic. Virologists, biologists, pharmacists, materials scientists, and clinicians are collaborating to develop efficient treatment strategies. Overall, in addition to the use of clinical equipment to assist...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Zhongmin, Zhang, Xingcai, Shu, Yiqing, Guo, Ming, Zhang, Han, Tao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640897/
https://www.ncbi.nlm.nih.gov/pubmed/33178330
http://dx.doi.org/10.1016/j.nantod.2020.101019
_version_ 1783605841801248768
author Tang, Zhongmin
Zhang, Xingcai
Shu, Yiqing
Guo, Ming
Zhang, Han
Tao, Wei
author_facet Tang, Zhongmin
Zhang, Xingcai
Shu, Yiqing
Guo, Ming
Zhang, Han
Tao, Wei
author_sort Tang, Zhongmin
collection PubMed
description In just a few months, SARS-CoV-2 and the disease it causes, COVID-19, created a worldwide pandemic. Virologists, biologists, pharmacists, materials scientists, and clinicians are collaborating to develop efficient treatment strategies. Overall, in addition to the use of clinical equipment to assist patient rehabilitation, antiviral drugs and vaccines are the areas of greatest focus. Given the physical size of SARS-CoV-2 and the vaccine delivery platforms currently in clinical trials, the relevance of nanotechnology is clear, and previous antiviral research using nanomaterials also supports this connection. Herein we briefly summarize current representative strategies regarding nanomaterials in antiviral research. We focus specifically on SARS-CoV-2 and the detailed role that nanotechnology can play in addressing this pandemic, including i) using FDA-approved nanomaterials for drug/vaccine delivery, including further exploration of the inhalation pathway; ii) introducing promising nanomaterials currently in clinical trials for drug/vaccine delivery; iii) designing novel biocompatible nanomaterials to combat the virus via interfering in its life cycle; and iv) promoting the utilization of nanomaterials in pneumonia treatment.
format Online
Article
Text
id pubmed-7640897
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-76408972020-11-05 Insights from nanotechnology in COVID-19 treatment Tang, Zhongmin Zhang, Xingcai Shu, Yiqing Guo, Ming Zhang, Han Tao, Wei Nano Today Opinion In just a few months, SARS-CoV-2 and the disease it causes, COVID-19, created a worldwide pandemic. Virologists, biologists, pharmacists, materials scientists, and clinicians are collaborating to develop efficient treatment strategies. Overall, in addition to the use of clinical equipment to assist patient rehabilitation, antiviral drugs and vaccines are the areas of greatest focus. Given the physical size of SARS-CoV-2 and the vaccine delivery platforms currently in clinical trials, the relevance of nanotechnology is clear, and previous antiviral research using nanomaterials also supports this connection. Herein we briefly summarize current representative strategies regarding nanomaterials in antiviral research. We focus specifically on SARS-CoV-2 and the detailed role that nanotechnology can play in addressing this pandemic, including i) using FDA-approved nanomaterials for drug/vaccine delivery, including further exploration of the inhalation pathway; ii) introducing promising nanomaterials currently in clinical trials for drug/vaccine delivery; iii) designing novel biocompatible nanomaterials to combat the virus via interfering in its life cycle; and iv) promoting the utilization of nanomaterials in pneumonia treatment. Elsevier Ltd. 2021-02 2020-11-04 /pmc/articles/PMC7640897/ /pubmed/33178330 http://dx.doi.org/10.1016/j.nantod.2020.101019 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Opinion
Tang, Zhongmin
Zhang, Xingcai
Shu, Yiqing
Guo, Ming
Zhang, Han
Tao, Wei
Insights from nanotechnology in COVID-19 treatment
title Insights from nanotechnology in COVID-19 treatment
title_full Insights from nanotechnology in COVID-19 treatment
title_fullStr Insights from nanotechnology in COVID-19 treatment
title_full_unstemmed Insights from nanotechnology in COVID-19 treatment
title_short Insights from nanotechnology in COVID-19 treatment
title_sort insights from nanotechnology in covid-19 treatment
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640897/
https://www.ncbi.nlm.nih.gov/pubmed/33178330
http://dx.doi.org/10.1016/j.nantod.2020.101019
work_keys_str_mv AT tangzhongmin insightsfromnanotechnologyincovid19treatment
AT zhangxingcai insightsfromnanotechnologyincovid19treatment
AT shuyiqing insightsfromnanotechnologyincovid19treatment
AT guoming insightsfromnanotechnologyincovid19treatment
AT zhanghan insightsfromnanotechnologyincovid19treatment
AT taowei insightsfromnanotechnologyincovid19treatment