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Insights from nanotechnology in COVID-19 treatment
In just a few months, SARS-CoV-2 and the disease it causes, COVID-19, created a worldwide pandemic. Virologists, biologists, pharmacists, materials scientists, and clinicians are collaborating to develop efficient treatment strategies. Overall, in addition to the use of clinical equipment to assist...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640897/ https://www.ncbi.nlm.nih.gov/pubmed/33178330 http://dx.doi.org/10.1016/j.nantod.2020.101019 |
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author | Tang, Zhongmin Zhang, Xingcai Shu, Yiqing Guo, Ming Zhang, Han Tao, Wei |
author_facet | Tang, Zhongmin Zhang, Xingcai Shu, Yiqing Guo, Ming Zhang, Han Tao, Wei |
author_sort | Tang, Zhongmin |
collection | PubMed |
description | In just a few months, SARS-CoV-2 and the disease it causes, COVID-19, created a worldwide pandemic. Virologists, biologists, pharmacists, materials scientists, and clinicians are collaborating to develop efficient treatment strategies. Overall, in addition to the use of clinical equipment to assist patient rehabilitation, antiviral drugs and vaccines are the areas of greatest focus. Given the physical size of SARS-CoV-2 and the vaccine delivery platforms currently in clinical trials, the relevance of nanotechnology is clear, and previous antiviral research using nanomaterials also supports this connection. Herein we briefly summarize current representative strategies regarding nanomaterials in antiviral research. We focus specifically on SARS-CoV-2 and the detailed role that nanotechnology can play in addressing this pandemic, including i) using FDA-approved nanomaterials for drug/vaccine delivery, including further exploration of the inhalation pathway; ii) introducing promising nanomaterials currently in clinical trials for drug/vaccine delivery; iii) designing novel biocompatible nanomaterials to combat the virus via interfering in its life cycle; and iv) promoting the utilization of nanomaterials in pneumonia treatment. |
format | Online Article Text |
id | pubmed-7640897 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76408972020-11-05 Insights from nanotechnology in COVID-19 treatment Tang, Zhongmin Zhang, Xingcai Shu, Yiqing Guo, Ming Zhang, Han Tao, Wei Nano Today Opinion In just a few months, SARS-CoV-2 and the disease it causes, COVID-19, created a worldwide pandemic. Virologists, biologists, pharmacists, materials scientists, and clinicians are collaborating to develop efficient treatment strategies. Overall, in addition to the use of clinical equipment to assist patient rehabilitation, antiviral drugs and vaccines are the areas of greatest focus. Given the physical size of SARS-CoV-2 and the vaccine delivery platforms currently in clinical trials, the relevance of nanotechnology is clear, and previous antiviral research using nanomaterials also supports this connection. Herein we briefly summarize current representative strategies regarding nanomaterials in antiviral research. We focus specifically on SARS-CoV-2 and the detailed role that nanotechnology can play in addressing this pandemic, including i) using FDA-approved nanomaterials for drug/vaccine delivery, including further exploration of the inhalation pathway; ii) introducing promising nanomaterials currently in clinical trials for drug/vaccine delivery; iii) designing novel biocompatible nanomaterials to combat the virus via interfering in its life cycle; and iv) promoting the utilization of nanomaterials in pneumonia treatment. Elsevier Ltd. 2021-02 2020-11-04 /pmc/articles/PMC7640897/ /pubmed/33178330 http://dx.doi.org/10.1016/j.nantod.2020.101019 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Opinion Tang, Zhongmin Zhang, Xingcai Shu, Yiqing Guo, Ming Zhang, Han Tao, Wei Insights from nanotechnology in COVID-19 treatment |
title | Insights from nanotechnology in COVID-19 treatment |
title_full | Insights from nanotechnology in COVID-19 treatment |
title_fullStr | Insights from nanotechnology in COVID-19 treatment |
title_full_unstemmed | Insights from nanotechnology in COVID-19 treatment |
title_short | Insights from nanotechnology in COVID-19 treatment |
title_sort | insights from nanotechnology in covid-19 treatment |
topic | Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640897/ https://www.ncbi.nlm.nih.gov/pubmed/33178330 http://dx.doi.org/10.1016/j.nantod.2020.101019 |
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