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Lactate dehydrogenase A inhibition by small molecular entities: steps in the right direction
Direct targeting of energy metabolism to defeat cancer is not a recent strategy. Although quite a few drugs use cellular metabolism for their antitumor effect, no direct inhibitors of energy metabolism have been approved by the FDA. Currently, several inhibitors of lactate dehydrogenase A (LDH-A), a...
Autores principales: | El Hassouni, Btissame, Franczak, Marika, Capula, Mjriam, Vonk, Christian M., Gomez, Valentina M., Smolenski, Ryszard T., Granchi, Carlotta, Peters, Godefridus J., Minutolo, Filippo, Giovannetti, Elisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640902/ https://www.ncbi.nlm.nih.gov/pubmed/33195739 http://dx.doi.org/10.18632/oncoscience.519 |
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