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Atomic Structures of Closed and Open Influenza B M2 Proton Channel Reveal the Conduction Mechanism
The influenza B M2 (BM2) proton channel is activated by acidic pH to mediate virus uncoating. Unlike influenza A M2 (AM2), which conducts protons with strong inward rectification, BM2 conducts protons both inward and outward. Here we report 1.4- and 1.5-angstrom solid-state NMR structures of the tra...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641042/ https://www.ncbi.nlm.nih.gov/pubmed/32015551 http://dx.doi.org/10.1038/s41594-019-0371-2 |