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Establishment and characterisation of testicular cancer patient-derived xenograft models for preclinical evaluation of novel therapeutic strategies

Testicular cancer (TC) is the most common solid tumour in young men. While cisplatin-based chemotherapy is highly effective in TC patients, chemoresistance still accounts for 10% of disease-related deaths. Pre-clinical models that faithfully reflect patient tumours are needed to assist in target dis...

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Detalles Bibliográficos
Autores principales:	de Vries, Gerda, Rosas-Plaza, Ximena, Meersma, Gert Jan, Leeuwenburgh, Vincent C., Kok, Klaas, Suurmeijer, Albert J. H., van Vugt, Marcel A. T. M., Gietema, Jourik A., de Jong, Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641131/ https://www.ncbi.nlm.nih.gov/pubmed/33144587 http://dx.doi.org/10.1038/s41598-020-75518-3

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