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A low-bias and sensitive small RNA library preparation method using randomized splint ligation
Small RNAs are important regulators of gene expression and are involved in human development and disease. Next generation sequencing (NGS) allows for scalable, genome-wide studies of small RNA; however, current methods are challenged by low sensitivity and high bias, limiting their ability to captur...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641310/ https://www.ncbi.nlm.nih.gov/pubmed/32496547 http://dx.doi.org/10.1093/nar/gkaa480 |