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RaptRanker: in silico RNA aptamer selection from HT-SELEX experiment based on local sequence and structure information

Aptamers are short single-stranded RNA/DNA molecules that bind to specific target molecules. Aptamers with high binding-affinity and target specificity are identified using an in vitro procedure called high throughput systematic evolution of ligands by exponential enrichment (HT-SELEX). However, the...

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Detalles Bibliográficos
Autores principales:	Ishida, Ryoga, Adachi, Tatsuo, Yokota, Aya, Yoshihara, Hidehito, Aoki, Kazuteru, Nakamura, Yoshikazu, Hamada, Michiaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641312/ https://www.ncbi.nlm.nih.gov/pubmed/32537639 http://dx.doi.org/10.1093/nar/gkaa484

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