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Secreted protein acidic and rich in cysteine (SPARC) knockout mice have greater outflow facility

PURPOSE: Secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein that regulates intraocular pressure (IOP) by altering extracellular matrix (ECM) homeostasis within the trabecular meshwork (TM). We hypothesized that the lower IOP previously observed in SPARC -/- mice is due t...

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Detalles Bibliográficos
Autores principales:	Yu, Ling, Zheng, Yuxi, Liu, Brian J., Kang, Min Hyung, Millar, J. Cameron, Rhee, Douglas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641442/ https://www.ncbi.nlm.nih.gov/pubmed/33147244 http://dx.doi.org/10.1371/journal.pone.0241294

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