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Investigating the trade-off between folding and function in a multidomain Y-family DNA polymerase

The way in which multidomain proteins fold has been a puzzling question for decades. Until now, the mechanisms and functions of domain interactions involved in multidomain protein folding have been obscure. Here, we develop structure-based models to investigate the folding and DNA-binding processes...

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Detalles Bibliográficos
Autores principales:	Chu, Xiakun, Suo, Zucai, Wang, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641590/ https://www.ncbi.nlm.nih.gov/pubmed/33079059 http://dx.doi.org/10.7554/eLife.60434

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