Modular metabolite assembly in Caenorhabditis elegans depends on carboxylesterases and formation of lysosome-related organelles

Signaling molecules derived from attachment of diverse metabolic building blocks to ascarosides play a central role in the life history of C. elegans and other nematodes; however, many aspects of their biogenesis remain unclear. Using comparative metabolomics, we show that a pathway mediating format...

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Detalles Bibliográficos
Autores principales: Le, Henry H, Wrobel, Chester JJ, Cohen, Sarah M, Yu, Jingfang, Park, Heenam, Helf, Maximilian J, Curtis, Brian J, Kruempel, Joseph C, Rodrigues, Pedro Reis, Hu, Patrick J, Sternberg, Paul W, Schroeder, Frank C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641594/
https://www.ncbi.nlm.nih.gov/pubmed/33063667
http://dx.doi.org/10.7554/eLife.61886

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