Increased Cytoplasmic CD138 Expression Is Associated with Aggressive Characteristics in Prostate Cancer and Is an Independent Predictor for Biochemical Recurrence

Syndecan-1 (CD138) is a transmembrane proteoglycan expressed in various normal and malignant tissues. It is of interest due to a possible prognostic effect in tumors and its role as a target for the antibody-drug conjugate indatuximab ravtansine. Here, we analyzed 17,747 prostate cancers by immunohi...

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Detalles Bibliográficos
Autores principales: Kind, Simon, Kluth, Martina, Hube-Magg, Claudia, Möller, Katharina, Makrypidi-Fraune, Georgia, Lutz, Florian, Lennartz, Maximilian, Rico, Sebastian Dwertmann, Schlomm, Thorsten, Heinzer, Hans, Höflmayer, Doris, Weidemann, Sören, Uhlig, Ria, Huland, Hartwig, Graefen, Markus, Bernreuther, Christian, Tsourlakis, Maria Christina, Minner, Sarah, Dum, David, Hinsch, Andrea, Lübke, Andreas M., Simon, Ronald, Sauter, Guido, Marx, Andreas, Polonski, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641694/
https://www.ncbi.nlm.nih.gov/pubmed/33195694
http://dx.doi.org/10.1155/2020/5845374

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