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A high-throughput alpha particle irradiation system for monitoring DNA damage repair, genome instability and screening in human cell and yeast model systems
Ionizing radiation (IR) is environmentally prevalent and, depending on dose and linear energy transfer (LET), can elicit serious health effects by damaging DNA. Relative to low LET photon radiation (X-rays, gamma rays), higher LET particle radiation produces more disease causing, complex DNA damage...
Autores principales: | Stanley, Fintan K T, Berger, N Daniel, Pearson, Dustin D, Danforth, John M, Morrison, Hali, Johnston, James E, Warnock, Tyler S, Brenner, Darren R, Chan, Jennifer A, Pierce, Greg, Cobb, Jennifer A, Ploquin, Nicolas P, Goodarzi, Aaron A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641727/ https://www.ncbi.nlm.nih.gov/pubmed/33010172 http://dx.doi.org/10.1093/nar/gkaa782 |
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