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A tissue-specific collaborative mixed model for jointly analyzing multiple tissues in transcriptome-wide association studies
Transcriptome-wide association studies (TWASs) integrate expression quantitative trait loci (eQTLs) studies with genome-wide association studies (GWASs) to prioritize candidate target genes for complex traits. Several statistical methods have been recently proposed to improve the performance of TWAS...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641735/ https://www.ncbi.nlm.nih.gov/pubmed/32978944 http://dx.doi.org/10.1093/nar/gkaa767 |