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A tissue-specific collaborative mixed model for jointly analyzing multiple tissues in transcriptome-wide association studies

Transcriptome-wide association studies (TWASs) integrate expression quantitative trait loci (eQTLs) studies with genome-wide association studies (GWASs) to prioritize candidate target genes for complex traits. Several statistical methods have been recently proposed to improve the performance of TWAS...

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Detalles Bibliográficos
Autores principales: Shi, Xingjie, Chai, Xiaoran, Yang, Yi, Cheng, Qing, Jiao, Yuling, Chen, Haoyue, Huang, Jian, Yang, Can, Liu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641735/
https://www.ncbi.nlm.nih.gov/pubmed/32978944
http://dx.doi.org/10.1093/nar/gkaa767