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Coexistence of two quadruplex–duplex hybrids in the PIM1 gene

The triple-negative breast cancer (TNBC), a subtype of breast cancer which lacks of targeted therapies, exhibits a poor prognosis. It was shown recently that the PIM1 oncogene is highly related to the proliferation of TNBC cells. A quadruplex–duplex hybrid (QDH) forming sequence was recently found t...

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Detalles Bibliográficos
Autores principales: Tan, Derrick J Y, Winnerdy, Fernaldo Richtia, Lim, Kah Wai, Phan, Anh Tuân
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641742/
https://www.ncbi.nlm.nih.gov/pubmed/32976598
http://dx.doi.org/10.1093/nar/gkaa752