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NBS1 interacts with Notch signaling in neuronal homeostasis

NBS1 is a critical component of the MRN (MRE11/RAD50/NBS1) complex, which regulates ATM- and ATR-mediated DNA damage response (DDR) pathways. Mutations in NBS1 cause the human genomic instability syndrome Nijmegen Breakage Syndrome (NBS), of which neuronal deficits, including microcephaly and intell...

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Detalles Bibliográficos
Autores principales:	Zhou, Zhong-Wei, Kirtay, Murat, Schneble, Nadine, Yakoub, George, Ding, Mingmei, Rüdiger, Tina, Siniuk, Kanstantsin, Lu, Ruiqing, Jiang, Yi-Nan, Li, Tang-Liang, Kaether, Christoph, Barzilai, Ari, Wang, Zhao-Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641754/ https://www.ncbi.nlm.nih.gov/pubmed/33010171 http://dx.doi.org/10.1093/nar/gkaa716

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