Mechanism of efficient double-strand break repair by a long non-coding RNA

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Mechanistic studies in DNA repair have focused on roles of multi-protein DNA complexes, so how long non-coding RNAs (lncRNAs) regulate DNA repair is less well understood. Yet, lncRNA LINP1 is over-expressed in multiple cancers and confers resistance to ionizing radiation and chemotherapeutic drugs....

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Detalles Bibliográficos
Autores principales: Thapar, Roopa, Wang, Jing L, Hammel, Michal, Ye, Ruiqiong, Liang, Ke, Sun, Chengcao, Hnizda, Ales, Liang, Shikang, Maw, Su S, Lee, Linda, Villarreal, Heather, Forrester, Isaac, Fang, Shujuan, Tsai, Miaw-Sheue, Blundell, Tom L, Davis, Anthony J, Lin, Chunru, Lees-Miller, Susan P, Strick, Terence R, Tainer, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641761/
https://www.ncbi.nlm.nih.gov/pubmed/33045735
http://dx.doi.org/10.1093/nar/gkaa784
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