Cargando…

MYC as a driver of stochastic chromatin networks: implications for the fitness of cancer cells

The relationship between stochastic transcriptional bursts and dynamic 3D chromatin states is not well understood. Using an innovated, ultra-sensitive technique, we address here enigmatic features underlying the communications between MYC and its enhancers in relation to the transcriptional process....

Descripción completa

Detalles Bibliográficos
Autores principales: Sumida, Noriyuki, Sifakis, Emmanouil G, Kiani, Narsis A, Ronnegren, Anna Lewandowska, Scholz, Barbara A, Vestlund, Johanna, Gomez-Cabrero, David, Tegner, Jesper, Göndör, Anita, Ohlsson, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641766/
https://www.ncbi.nlm.nih.gov/pubmed/33051686
http://dx.doi.org/10.1093/nar/gkaa817