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Senescence-activated enhancer landscape orchestrates the senescence-associated secretory phenotype in murine fibroblasts
The three-dimensional configuration of the chromatin architecture is known to be crucial for alterations in the transcriptional network; however, the underlying mechanisms of epigenetic control of senescence-related gene expression by modulating the chromatin architecture remain unknown. Here, we de...
Autores principales: | Guan, Yiting, Zhang, Chao, Lyu, Guoliang, Huang, Xiaoke, Zhang, Xuebin, Zhuang, Tenghan, Jia, Lumeng, Zhang, Lijun, Zhang, Chen, Li, Cheng, Tao, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641768/ https://www.ncbi.nlm.nih.gov/pubmed/33045748 http://dx.doi.org/10.1093/nar/gkaa858 |
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