Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system

The two-gene module HEPN/MNT is predicted to be the most abundant toxin/antitoxin (TA) system in prokaryotes. However, its physiological function and neutralization mechanism remains obscure. Here, we discovered that the MntA antitoxin (MNT-domain protein) acts as an adenylyltransferase and chemical...

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Detalles Bibliográficos
Autores principales: Yao, Jianyun, Zhen, Xiangkai, Tang, Kaihao, Liu, Tianlang, Xu, Xiaolong, Chen, Zhe, Guo, Yunxue, Liu, Xiaoxiao, Wood, Thomas K, Ouyang, Songying, Wang, Xiaoxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641770/
https://www.ncbi.nlm.nih.gov/pubmed/33045733
http://dx.doi.org/10.1093/nar/gkaa855

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