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Hypermethylation of LATS2 Promoter and Its Prognostic Value in IDH-Mutated Low-Grade Gliomas

Mutations in the enzyme isocitrate dehydrogenase 1/2 (IDH1/2) are the most common somatic mutations in low-grade glioma (LGG). The Hippo signaling pathway is known to play a key role in organ size control, and its dysregulation is involved in the development of diverse cancers. Large tumor suppresso...

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Detalles Bibliográficos
Autores principales: Gu, Yuan, Wang, Yu, Wang, Yebin, Luo, Jiaqian, Wang, Xin, Ma, Mingyue, Hua, Wei, Liu, Ying, Yu, Fa-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642219/
https://www.ncbi.nlm.nih.gov/pubmed/33195240
http://dx.doi.org/10.3389/fcell.2020.586581

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