Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype

The tumour microenvironment plays a crucial role in the growth and progression of cancer, and the presence of tumour-associated macrophages (TAMs) is associated with poor prognosis. Recent studies have demonstrated that TAMs display transcriptomic, phenotypic, functional and geographical diversity....

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Detalles Bibliográficos
Autores principales: Beatson, Richard, Graham, Rosalind, Grundland Freile, Fabio, Cozzetto, Domenico, Kannambath, Shichina, Pfeifer, Ester, Woodman, Natalie, Owen, Julie, Nuamah, Rosamond, Mandel, Ulla, Pinder, Sarah, Gillett, Cheryl, Noll, Thomas, Bouybayoune, Ihssane, Taylor-Papadimitriou, Joyce, Burchell, Joy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642421/
https://www.ncbi.nlm.nih.gov/pubmed/33149188
http://dx.doi.org/10.1038/s42003-020-01359-5

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