Reconstitution of rat fetal testis during the masculinisation programming window induces focal dysgenesis consistent with testicular dysgenesis syndrome

Focal dysgenesis is a consistent feature of testicular dysgenesis syndrome (TDS) in humans. Rodent studies show that perturbation of androgens (e.g. following phthalate exposure) during a fetal masculinisation programming window (MPW) predisposes to a TDS phenotype. This study aimed to determine whe...

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Detalles Bibliográficos
Autores principales: Smart, Ellie, Macdonald, Joni, Smith, Lee B., Mitchell, Rod T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642428/
https://www.ncbi.nlm.nih.gov/pubmed/33149175
http://dx.doi.org/10.1038/s41598-020-75803-1

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