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Association Between Occlusion Type and Etiology of Acute Intracranial Large Artery Occlusion
Objective: To investigate the diagnostic efficiency of truncal-type occlusion and branching-site occlusion in determining the etiology of intracranial large artery occlusion related acute ischemic stroke (AIS). Methods: Patients with intracranial large artery occlusion related AIS who received stent...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642447/ https://www.ncbi.nlm.nih.gov/pubmed/33193040 http://dx.doi.org/10.3389/fneur.2020.582388 |
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author | Chuming, Huang Yifan, Hong Ke, Xu Chukai, Xu Weijie, Zhang Hui, Li Guoyi, Peng Xiaoyong, Zhang Peifeng, Zhang Chuwei, Cai |
author_facet | Chuming, Huang Yifan, Hong Ke, Xu Chukai, Xu Weijie, Zhang Hui, Li Guoyi, Peng Xiaoyong, Zhang Peifeng, Zhang Chuwei, Cai |
author_sort | Chuming, Huang |
collection | PubMed |
description | Objective: To investigate the diagnostic efficiency of truncal-type occlusion and branching-site occlusion in determining the etiology of intracranial large artery occlusion related acute ischemic stroke (AIS). Methods: Patients with intracranial large artery occlusion related AIS who received stent retriever (SR) thrombectomy from November 2014 to June 2019 were included in the study. All patients underwent angiography before SR thrombectomy, which was used to evaluate the occlusion type. Differences in the distribution of occlusion types in intracranial atherosclerosis (ICAS) and embolism were assessed, and the diagnostic indicators, including the area under the ROC curve (AUC), sensitivity, and specificity were calculated. Results: Of the 115 AIS patients with intracranial large artery occlusion, 42 were classified as having ICAS, and 73 having an embolism. In the ICAS group, branching-site occlusion was responsible for 3 (7%) cases and truncal-type occlusion for 39 (93%) cases, while in the embolism group, branching-site occlusion was responsible for 66 (90%) cases and truncal-type occlusion for 7 (10%) cases; the difference was statistically significant (all P < 0.01). The AUC for ICAS predicted by truncal-type occlusion was 0.916, with a sensitivity of 92.86%, and specificity of 90.41%. Conclusion: Truncal-type occlusion showed a high predictability of ICAS. Determine the etiology of intracranial large artery occlusion related AIS before SR thrombectomy may be most helpful in setting up optimal endovascular treatment strategies. |
format | Online Article Text |
id | pubmed-7642447 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76424472020-11-13 Association Between Occlusion Type and Etiology of Acute Intracranial Large Artery Occlusion Chuming, Huang Yifan, Hong Ke, Xu Chukai, Xu Weijie, Zhang Hui, Li Guoyi, Peng Xiaoyong, Zhang Peifeng, Zhang Chuwei, Cai Front Neurol Neurology Objective: To investigate the diagnostic efficiency of truncal-type occlusion and branching-site occlusion in determining the etiology of intracranial large artery occlusion related acute ischemic stroke (AIS). Methods: Patients with intracranial large artery occlusion related AIS who received stent retriever (SR) thrombectomy from November 2014 to June 2019 were included in the study. All patients underwent angiography before SR thrombectomy, which was used to evaluate the occlusion type. Differences in the distribution of occlusion types in intracranial atherosclerosis (ICAS) and embolism were assessed, and the diagnostic indicators, including the area under the ROC curve (AUC), sensitivity, and specificity were calculated. Results: Of the 115 AIS patients with intracranial large artery occlusion, 42 were classified as having ICAS, and 73 having an embolism. In the ICAS group, branching-site occlusion was responsible for 3 (7%) cases and truncal-type occlusion for 39 (93%) cases, while in the embolism group, branching-site occlusion was responsible for 66 (90%) cases and truncal-type occlusion for 7 (10%) cases; the difference was statistically significant (all P < 0.01). The AUC for ICAS predicted by truncal-type occlusion was 0.916, with a sensitivity of 92.86%, and specificity of 90.41%. Conclusion: Truncal-type occlusion showed a high predictability of ICAS. Determine the etiology of intracranial large artery occlusion related AIS before SR thrombectomy may be most helpful in setting up optimal endovascular treatment strategies. Frontiers Media S.A. 2020-10-22 /pmc/articles/PMC7642447/ /pubmed/33193040 http://dx.doi.org/10.3389/fneur.2020.582388 Text en Copyright © 2020 Chuming, Yifan, Ke, Chukai, Weijie, Hui, Guoyi, Xiaoyong, Peifeng and Chuwei. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Chuming, Huang Yifan, Hong Ke, Xu Chukai, Xu Weijie, Zhang Hui, Li Guoyi, Peng Xiaoyong, Zhang Peifeng, Zhang Chuwei, Cai Association Between Occlusion Type and Etiology of Acute Intracranial Large Artery Occlusion |
title | Association Between Occlusion Type and Etiology of Acute Intracranial Large Artery Occlusion |
title_full | Association Between Occlusion Type and Etiology of Acute Intracranial Large Artery Occlusion |
title_fullStr | Association Between Occlusion Type and Etiology of Acute Intracranial Large Artery Occlusion |
title_full_unstemmed | Association Between Occlusion Type and Etiology of Acute Intracranial Large Artery Occlusion |
title_short | Association Between Occlusion Type and Etiology of Acute Intracranial Large Artery Occlusion |
title_sort | association between occlusion type and etiology of acute intracranial large artery occlusion |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642447/ https://www.ncbi.nlm.nih.gov/pubmed/33193040 http://dx.doi.org/10.3389/fneur.2020.582388 |
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