Cargando…
Antibody-Dependent Enhancement: A Challenge for Developing a Safe Dengue Vaccine
In 2019, the United States Food and Drug Administration accorded restricted approval to Sanofi Pasteur's Dengvaxia, a live attenuated vaccine (LAV) for dengue fever, a mosquito-borne viral disease, caused by four antigenically distinct dengue virus serotypes (DENV 1-4). The reason for this limi...
Autores principales: | Shukla, Rahul, Ramasamy, Viswanathan, Shanmugam, Rajgokul K., Ahuja, Richa, Khanna, Navin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642463/ https://www.ncbi.nlm.nih.gov/pubmed/33194810 http://dx.doi.org/10.3389/fcimb.2020.572681 |
Ejemplares similares
-
Dengue and Zika virus infections are enhanced by live attenuated dengue vaccine but not by recombinant DSV4 vaccine candidate in mouse models
por: Shukla, Rahul, et al.
Publicado: (2020) -
Intrinsic ADE: The Dark Side of Antibody Dependent Enhancement During Dengue Infection
por: Narayan, Rohan, et al.
Publicado: (2020) -
Zika virus envelope nanoparticle antibodies protect mice without risk of disease enhancement
por: Shukla, Rahul, et al.
Publicado: (2020) -
Molecular Simulations Reveal the Role of Antibody Fine Specificity and Viral Maturation State on Antibody-Dependent Enhancement of Infection in Dengue Virus
por: Ripoll, Daniel R., et al.
Publicado: (2019) -
Cellular T-cell immune response profiling by tetravalent dengue subunit vaccine (DSV4) candidate in mice
por: Aggarwal, Charu, et al.
Publicado: (2023)