Cargando…
Paraprobiotics and Postbiotics of Probiotic Lactobacilli, Their Positive Effects on the Host and Action Mechanisms: A Review
Lactobacilli comprise an important group of probiotics for both human and animals. The emerging concern regarding safety problems associated with live microbial cells is enhancing the interest in using cell components and metabolites derived from probiotic strains. Here, we define cell structural co...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642493/ https://www.ncbi.nlm.nih.gov/pubmed/33195367 http://dx.doi.org/10.3389/fnut.2020.570344 |
_version_ | 1783606097954734080 |
---|---|
author | Teame, Tsegay Wang, Anran Xie, Mingxu Zhang, Zhen Yang, Yalin Ding, Qianwen Gao, Chenchen Olsen, Rolf Erik Ran, Chao Zhou, Zhigang |
author_facet | Teame, Tsegay Wang, Anran Xie, Mingxu Zhang, Zhen Yang, Yalin Ding, Qianwen Gao, Chenchen Olsen, Rolf Erik Ran, Chao Zhou, Zhigang |
author_sort | Teame, Tsegay |
collection | PubMed |
description | Lactobacilli comprise an important group of probiotics for both human and animals. The emerging concern regarding safety problems associated with live microbial cells is enhancing the interest in using cell components and metabolites derived from probiotic strains. Here, we define cell structural components and metabolites of probiotic bacteria as paraprobiotics and postbiotics, respectively. Paraprobiotics and postbiotics produced from Lactobacilli consist of a wide range of molecules including peptidoglycans, surface proteins, cell wall polysaccharides, secreted proteins, bacteriocins, and organic acids, which mediate positive effect on the host, such as immunomodulatory, anti-tumor, antimicrobial, and barrier-preservation effects. In this review, we systematically summarize the paraprobiotics and postbiotics derived from Lactobacilli and their beneficial functions. We also discuss the mechanisms underlying their beneficial effects on the host, and their interaction with the host cells. This review may boost our understanding on the benefits and molecular mechanisms associated with paraprobiotics and probiotics from Lactobacilli, which may promote their applications in humans and animals. |
format | Online Article Text |
id | pubmed-7642493 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76424932020-11-13 Paraprobiotics and Postbiotics of Probiotic Lactobacilli, Their Positive Effects on the Host and Action Mechanisms: A Review Teame, Tsegay Wang, Anran Xie, Mingxu Zhang, Zhen Yang, Yalin Ding, Qianwen Gao, Chenchen Olsen, Rolf Erik Ran, Chao Zhou, Zhigang Front Nutr Nutrition Lactobacilli comprise an important group of probiotics for both human and animals. The emerging concern regarding safety problems associated with live microbial cells is enhancing the interest in using cell components and metabolites derived from probiotic strains. Here, we define cell structural components and metabolites of probiotic bacteria as paraprobiotics and postbiotics, respectively. Paraprobiotics and postbiotics produced from Lactobacilli consist of a wide range of molecules including peptidoglycans, surface proteins, cell wall polysaccharides, secreted proteins, bacteriocins, and organic acids, which mediate positive effect on the host, such as immunomodulatory, anti-tumor, antimicrobial, and barrier-preservation effects. In this review, we systematically summarize the paraprobiotics and postbiotics derived from Lactobacilli and their beneficial functions. We also discuss the mechanisms underlying their beneficial effects on the host, and their interaction with the host cells. This review may boost our understanding on the benefits and molecular mechanisms associated with paraprobiotics and probiotics from Lactobacilli, which may promote their applications in humans and animals. Frontiers Media S.A. 2020-10-22 /pmc/articles/PMC7642493/ /pubmed/33195367 http://dx.doi.org/10.3389/fnut.2020.570344 Text en Copyright © 2020 Teame, Wang, Xie, Zhang, Yang, Ding, Gao, Olsen, Ran and Zhou. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Nutrition Teame, Tsegay Wang, Anran Xie, Mingxu Zhang, Zhen Yang, Yalin Ding, Qianwen Gao, Chenchen Olsen, Rolf Erik Ran, Chao Zhou, Zhigang Paraprobiotics and Postbiotics of Probiotic Lactobacilli, Their Positive Effects on the Host and Action Mechanisms: A Review |
title | Paraprobiotics and Postbiotics of Probiotic Lactobacilli, Their Positive Effects on the Host and Action Mechanisms: A Review |
title_full | Paraprobiotics and Postbiotics of Probiotic Lactobacilli, Their Positive Effects on the Host and Action Mechanisms: A Review |
title_fullStr | Paraprobiotics and Postbiotics of Probiotic Lactobacilli, Their Positive Effects on the Host and Action Mechanisms: A Review |
title_full_unstemmed | Paraprobiotics and Postbiotics of Probiotic Lactobacilli, Their Positive Effects on the Host and Action Mechanisms: A Review |
title_short | Paraprobiotics and Postbiotics of Probiotic Lactobacilli, Their Positive Effects on the Host and Action Mechanisms: A Review |
title_sort | paraprobiotics and postbiotics of probiotic lactobacilli, their positive effects on the host and action mechanisms: a review |
topic | Nutrition |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642493/ https://www.ncbi.nlm.nih.gov/pubmed/33195367 http://dx.doi.org/10.3389/fnut.2020.570344 |
work_keys_str_mv | AT teametsegay paraprobioticsandpostbioticsofprobioticlactobacillitheirpositiveeffectsonthehostandactionmechanismsareview AT wanganran paraprobioticsandpostbioticsofprobioticlactobacillitheirpositiveeffectsonthehostandactionmechanismsareview AT xiemingxu paraprobioticsandpostbioticsofprobioticlactobacillitheirpositiveeffectsonthehostandactionmechanismsareview AT zhangzhen paraprobioticsandpostbioticsofprobioticlactobacillitheirpositiveeffectsonthehostandactionmechanismsareview AT yangyalin paraprobioticsandpostbioticsofprobioticlactobacillitheirpositiveeffectsonthehostandactionmechanismsareview AT dingqianwen paraprobioticsandpostbioticsofprobioticlactobacillitheirpositiveeffectsonthehostandactionmechanismsareview AT gaochenchen paraprobioticsandpostbioticsofprobioticlactobacillitheirpositiveeffectsonthehostandactionmechanismsareview AT olsenrolferik paraprobioticsandpostbioticsofprobioticlactobacillitheirpositiveeffectsonthehostandactionmechanismsareview AT ranchao paraprobioticsandpostbioticsofprobioticlactobacillitheirpositiveeffectsonthehostandactionmechanismsareview AT zhouzhigang paraprobioticsandpostbioticsofprobioticlactobacillitheirpositiveeffectsonthehostandactionmechanismsareview |