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Exome sequencing identifies frequent genomic loss of TET1 in IDH-wild-type glioblastoma()()

Glioblastoma (GBM) is the most common and malignant brain tumor in adults. Genomic and epigenomic alterations of multiple cancer-driving genes are frequent in GBM. To identify molecular alterations associated with epigenetic aberrations, we performed whole exome sequencing-based analysis of DNA copy...

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Detalles Bibliográficos
Autores principales: Stasik, Sebastian, Juratli, Tareq A., Petzold, Andreas, Richter, Sven, Zolal, Amir, Schackert, Gabriele, Dahl, Andreas, Krex, Dietmar, Thiede, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642757/
https://www.ncbi.nlm.nih.gov/pubmed/33142244
http://dx.doi.org/10.1016/j.neo.2020.10.010