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Exome sequencing identifies frequent genomic loss of TET1 in IDH-wild-type glioblastoma()()
Glioblastoma (GBM) is the most common and malignant brain tumor in adults. Genomic and epigenomic alterations of multiple cancer-driving genes are frequent in GBM. To identify molecular alterations associated with epigenetic aberrations, we performed whole exome sequencing-based analysis of DNA copy...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Neoplasia Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642757/ https://www.ncbi.nlm.nih.gov/pubmed/33142244 http://dx.doi.org/10.1016/j.neo.2020.10.010 |