Binding of the small-molecule kinase inhibitor ruxolitinib to membranes does not disturb membrane integrity

Ruxolitinib is a small-molecule protein kinase inhibitor, which is used as a therapeutic agent against several diseases. Due to its anti-inflammatory impact, ruxolitinib has also been considered recently for usage in the treatment of Covid-19. While the specific effects of ruxolitinib on Janus kinas...

Descripción completa

Detalles Bibliográficos
Autores principales: Fischer, Markus, Luck, Meike, Werle, Maximilian, Scheidt, Holger A., Müller, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642770/
https://www.ncbi.nlm.nih.gov/pubmed/33195828
http://dx.doi.org/10.1016/j.bbrep.2020.100838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642770/
https://www.ncbi.nlm.nih.gov/pubmed/33195828
http://dx.doi.org/10.1016/j.bbrep.2020.100838

Ejemplares similares