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Cortisone and cortisol break hydrogen-bonding rules to make a drug–prodrug solid solution

Multidrug products enable more effective therapies and simpler administration regimens, provided that a stable formulation is prepared, with the desired composition. In this view, solid solutions have the advantage of combining the stability of a single crystalline phase with the potential of stoich...

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Detalles Bibliográficos
Autores principales: Verma, Vivek, Bordignon, Simone, Chierotti, Michele R., Lestari, Monica, Lyons, Kieran, Padrela, Luis, Ryan, Kevin M., Lusi, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642785/
https://www.ncbi.nlm.nih.gov/pubmed/33209323
http://dx.doi.org/10.1107/S2052252520013263