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Structural insights into the effect of active-site mutation on the catalytic mechanism of carbonic anhydrase
Enzymes are catalysts of biological processes. Significant insight into their catalytic mechanisms has been obtained by relating site-directed mutagenesis studies to kinetic activity assays. However, revealing the detailed relationship between structural modifications and functional changes remains...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642793/ https://www.ncbi.nlm.nih.gov/pubmed/33209313 http://dx.doi.org/10.1107/S2052252520011008 |