A Specific IL6 Polymorphic Genotype Modulates the Risk of Trypanosoma cruzi Parasitemia While IL18, IL17A, and IL1B Variant Profiles and HIV Infection Protect Against Cardiomyopathy in Chagas Disease

BACKGROUND: Chagas disease caused by Trypanosoma cruzi (T. cruzi) affects approximately six million individuals worldwide. Clinical manifestations are expected to occur due to the parasite persistence and host immune response. Herein we investigated potential associations between IL1B, IL6, IL17A, o...

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Detalles Bibliográficos
Autores principales: Gomes dos Santos, Alexandra, Watanabe, Elieser Hitoshi, Ferreira, Daiane Tomomi, Oliveira, Jamille, Nakanishi, Érika Shimoda, Oliveira, Claudia Silva, Bocchi, Edimar, Novaes, Cristina Terra Gallafrio, Cruz, Fatima, Carvalho, Noemia Barbosa, Sato, Paula Keiko, Yamashiro-Kanashiro, Edite Hatsumi, Pontillo, Alessandra, de Freitas, Vera Lucia Teixeira, Onuchic, Luiz Fernando, Shikanai-Yasuda, Maria Aparecida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642879/
https://www.ncbi.nlm.nih.gov/pubmed/33193300
http://dx.doi.org/10.3389/fimmu.2020.521409

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