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Maximum a posteriori Threshold Genomic Prediction Model for Ordinal Traits

Due to the ever-increasing data collected in genomic breeding programs, there is a need for genomic prediction models that can deal better with big data. For this reason, here we propose a Maximum a posteriori Threshold Genomic Prediction (MAPT) model for ordinal traits that is more efficient than t...

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Autores principales: Montesinos-López, Abelardo, Gutierrez-Pulido, Humberto, Montesinos-López, Osval Antonio, Crossa, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642945/
https://www.ncbi.nlm.nih.gov/pubmed/32934017
http://dx.doi.org/10.1534/g3.120.401733
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author Montesinos-López, Abelardo
Gutierrez-Pulido, Humberto
Montesinos-López, Osval Antonio
Crossa, José
author_facet Montesinos-López, Abelardo
Gutierrez-Pulido, Humberto
Montesinos-López, Osval Antonio
Crossa, José
author_sort Montesinos-López, Abelardo
collection PubMed
description Due to the ever-increasing data collected in genomic breeding programs, there is a need for genomic prediction models that can deal better with big data. For this reason, here we propose a Maximum a posteriori Threshold Genomic Prediction (MAPT) model for ordinal traits that is more efficient than the conventional Bayesian Threshold Genomic Prediction model for ordinal traits. The MAPT performs the predictions of the Threshold Genomic Prediction model by using the maximum a posteriori estimation of the parameters, that is, the values of the parameters that maximize the joint posterior density. We compared the prediction performance of the proposed MAPT to the conventional Bayesian Threshold Genomic Prediction model, the multinomial Ridge regression and support vector machine on 8 real data sets. We found that the proposed MAPT was competitive with regard to the multinomial and support vector machine models in terms of prediction performance, and slightly better than the conventional Bayesian Threshold Genomic Prediction model. With regard to the implementation time, we found that in general the MAPT and the support vector machine were the best, while the slowest was the multinomial Ridge regression model. However, it is important to point out that the successful implementation of the proposed MAPT model depends on the informative priors used to avoid underestimation of variance components.
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spelling pubmed-76429452020-11-13 Maximum a posteriori Threshold Genomic Prediction Model for Ordinal Traits Montesinos-López, Abelardo Gutierrez-Pulido, Humberto Montesinos-López, Osval Antonio Crossa, José G3 (Bethesda) Genomic Prediction Due to the ever-increasing data collected in genomic breeding programs, there is a need for genomic prediction models that can deal better with big data. For this reason, here we propose a Maximum a posteriori Threshold Genomic Prediction (MAPT) model for ordinal traits that is more efficient than the conventional Bayesian Threshold Genomic Prediction model for ordinal traits. The MAPT performs the predictions of the Threshold Genomic Prediction model by using the maximum a posteriori estimation of the parameters, that is, the values of the parameters that maximize the joint posterior density. We compared the prediction performance of the proposed MAPT to the conventional Bayesian Threshold Genomic Prediction model, the multinomial Ridge regression and support vector machine on 8 real data sets. We found that the proposed MAPT was competitive with regard to the multinomial and support vector machine models in terms of prediction performance, and slightly better than the conventional Bayesian Threshold Genomic Prediction model. With regard to the implementation time, we found that in general the MAPT and the support vector machine were the best, while the slowest was the multinomial Ridge regression model. However, it is important to point out that the successful implementation of the proposed MAPT model depends on the informative priors used to avoid underestimation of variance components. Genetics Society of America 2020-09-15 /pmc/articles/PMC7642945/ /pubmed/32934017 http://dx.doi.org/10.1534/g3.120.401733 Text en Copyright © 2020 Montesinos-Lopez et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Genomic Prediction
Montesinos-López, Abelardo
Gutierrez-Pulido, Humberto
Montesinos-López, Osval Antonio
Crossa, José
Maximum a posteriori Threshold Genomic Prediction Model for Ordinal Traits
title Maximum a posteriori Threshold Genomic Prediction Model for Ordinal Traits
title_full Maximum a posteriori Threshold Genomic Prediction Model for Ordinal Traits
title_fullStr Maximum a posteriori Threshold Genomic Prediction Model for Ordinal Traits
title_full_unstemmed Maximum a posteriori Threshold Genomic Prediction Model for Ordinal Traits
title_short Maximum a posteriori Threshold Genomic Prediction Model for Ordinal Traits
title_sort maximum a posteriori threshold genomic prediction model for ordinal traits
topic Genomic Prediction
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642945/
https://www.ncbi.nlm.nih.gov/pubmed/32934017
http://dx.doi.org/10.1534/g3.120.401733
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