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Polygenic Scores for Height in Admixed Populations

Polygenic risk scores (PRS) use the results of genome-wide association studies (GWAS) to predict quantitative phenotypes or disease risk at an individual level, and provide a potential route to the use of genetic data in personalized medical care. However, a major barrier to the use of PRS is that t...

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Detalles Bibliográficos
Autores principales: Bitarello, Bárbara D., Mathieson, Iain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642950/
https://www.ncbi.nlm.nih.gov/pubmed/32878958
http://dx.doi.org/10.1534/g3.120.401658