De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors

Cancer immunotherapies using monoclonal antibodies to block inhibitory checkpoints are showing durable remissions in many types of cancer patients, although the majority of breast cancer patients acquire little benefit. Human melanoma and lung cancer patient studies suggest that immune checkpoint in...

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Detalles Bibliográficos
Autores principales: Workenhe, Samuel T., Nguyen, Andrew, Bakhshinyan, David, Wei, Jiarun, Hare, David N., MacNeill, Kelly L., Wan, Yonghong, Oberst, Andrew, Bramson, Jonathan L., Nasir, Jalees A., Vito, Alyssa, El-Sayes, Nader, Singh, Sheila K., McArthur, Andrew G., Mossman, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643076/
https://www.ncbi.nlm.nih.gov/pubmed/33149194
http://dx.doi.org/10.1038/s42003-020-01362-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643076/
https://www.ncbi.nlm.nih.gov/pubmed/33149194
http://dx.doi.org/10.1038/s42003-020-01362-w

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