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De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors
Cancer immunotherapies using monoclonal antibodies to block inhibitory checkpoints are showing durable remissions in many types of cancer patients, although the majority of breast cancer patients acquire little benefit. Human melanoma and lung cancer patient studies suggest that immune checkpoint in...
Autores principales: | Workenhe, Samuel T., Nguyen, Andrew, Bakhshinyan, David, Wei, Jiarun, Hare, David N., MacNeill, Kelly L., Wan, Yonghong, Oberst, Andrew, Bramson, Jonathan L., Nasir, Jalees A., Vito, Alyssa, El-Sayes, Nader, Singh, Sheila K., McArthur, Andrew G., Mossman, Karen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643076/ https://www.ncbi.nlm.nih.gov/pubmed/33149194 http://dx.doi.org/10.1038/s42003-020-01362-w |
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