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Coexistence of perseveration and apathy in the TDP-43(Q331K) knock-in mouse model of ALS–FTD
Perseveration and apathy are two of the most common behavioural and psychological symptoms of dementia (BPSDs) in amyotrophic lateral sclerosis–frontotemporal dementia (ALS–FTD). Availability of a validated and behaviourally characterised animal model is crucial for translational research into BPSD...
Autores principales: | Kim, Eosu, White, Matthew A., Phillips, Benjamin U., Lopez-Cruz, Laura, Kim, Hyunjeong, Heath, Christopher J., Lee, Jong Eun, Saksida, Lisa M., Sreedharan, Jemeen, Bussey, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643138/ https://www.ncbi.nlm.nih.gov/pubmed/33149110 http://dx.doi.org/10.1038/s41398-020-01078-9 |
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