Synthesis, crystal structure, Hirshfeld surface analysis, MEP study and mol­ecular docking of N-{3-[(4-meth­oxy­phen­yl)carbamo­yl]phen­yl}-3-nitro­benzamide as a promising inhibitor of hfXa

The title compound, C(21)H(17)N(3)O(5), consists of three rings, A, B and C, linked by amide bonds with the benzene rings A and C being inclined to the mean plane of the central benzene ring B by 2.99 (18) and 4.57 (18)°, respectively. In the crystal, mol­ecules are linked via N—H⋯O and C—H⋯O hydrog...

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Detalles Bibliográficos
Autores principales: Moreno-Fuquen, Rodolfo, Hurtado-Angulo, Mario, Arango-Daraviña, Kevin, Bain, Gavin, Kennedy, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2020
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643242/
https://www.ncbi.nlm.nih.gov/pubmed/33209349
http://dx.doi.org/10.1107/S2056989020013730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643242/
https://www.ncbi.nlm.nih.gov/pubmed/33209349
http://dx.doi.org/10.1107/S2056989020013730

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