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Equilibrium Binding Model for CpG DNA-Dependent Dimerization of Toll-like Receptor 9 Ectodomain

[Image: see text] Microbial nucleic acids in the extracellular milieu are recognized in vertebrates by Toll-like receptors (TLRs), one of the most important families of innate immune receptors. TLR9 recognizes single-stranded unmethylated CpG DNA in endosomes. DNA binding induces TLR9 dimerization a...

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Detalles Bibliográficos
Autores principales:	Reikine, Stephanie, McLaughlin, Stephen H., Modis, Yorgo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643339/ https://www.ncbi.nlm.nih.gov/pubmed/32818369 http://dx.doi.org/10.1021/acs.biochem.0c00466

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