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Rapid and Efficient Microwave‐Assisted Friedländer Quinoline Synthesis
A microwave‐based methodology facilitates reaction of 2‐aminophenylketones with cyclic ketones to form a quinoline scaffold. Syntheses of amido‐ and amino‐linked 17β‐hydroxysteroid dehydrogenase type 3 inhibitors with a benzophenone‐linked motif were pursued using 2‐aminobenzophenone as building blo...
Autores principales: | Bailey, Helen V., Mahon, Mary F., Vicker, Nigel, Potter, Barry V. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643340/ https://www.ncbi.nlm.nih.gov/pubmed/33194530 http://dx.doi.org/10.1002/open.202000247 |
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