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Gallbladder cancer-associated fibroblasts promote vasculogenic mimicry formation and tumor growth in gallbladder cancer via upregulating the expression of NOX4, a poor prognosis factor, through IL-6-JAK-STAT3 signal pathway

BACKGROUND: Cancer-associated fibroblasts (CAFs) and vasculogenic mimicry (VM) play important roles in the occurrence and development of tumors. However, the relationship between CAFs and VM formation, especially in gallbladder cancer (GBC) has not been clarified. In this study, we investigated whet...

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Detalles Bibliográficos
Autores principales: Pan, Mu-Su, Wang, Hui, Ansari, Kamar Hasan, Li, Xin-Ping, Sun, Wei, Fan, Yue-Zu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643415/
https://www.ncbi.nlm.nih.gov/pubmed/33153467
http://dx.doi.org/10.1186/s13046-020-01742-4

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