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Gallbladder cancer-associated fibroblasts promote vasculogenic mimicry formation and tumor growth in gallbladder cancer via upregulating the expression of NOX4, a poor prognosis factor, through IL-6-JAK-STAT3 signal pathway
BACKGROUND: Cancer-associated fibroblasts (CAFs) and vasculogenic mimicry (VM) play important roles in the occurrence and development of tumors. However, the relationship between CAFs and VM formation, especially in gallbladder cancer (GBC) has not been clarified. In this study, we investigated whet...
Autores principales: | Pan, Mu-Su, Wang, Hui, Ansari, Kamar Hasan, Li, Xin-Ping, Sun, Wei, Fan, Yue-Zu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643415/ https://www.ncbi.nlm.nih.gov/pubmed/33153467 http://dx.doi.org/10.1186/s13046-020-01742-4 |
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