Melphalan induces cardiotoxicity through oxidative stress in cardiomyocytes derived from human induced pluripotent stem cells

BACKGROUND: Treatment-induced cardiotoxicity is a leading noncancer-related cause of acute and late onset morbidity and mortality in cancer patients on antineoplastic drugs such as melphalan—increasing clinical case reports have documented that it could induce cardiotoxicity including severe arrhyth...

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Detalles Bibliográficos
Autores principales: Liu, Rui, Li, Dong, Sun, Fangxu, Rampoldi, Antonio, Maxwell, Joshua T., Wu, Ronghu, Fischbach, Peter, Castellino, Sharon M., Du, Yuhong, Fu, Haian, Mandawat, Anant, Xu, Chunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643439/
https://www.ncbi.nlm.nih.gov/pubmed/33153480
http://dx.doi.org/10.1186/s13287-020-01984-1

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