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APOE4 is associated with cognitive and pathological heterogeneity in patients with Alzheimer’s disease: a systematic review

Possession of the ε4 allele of apolipoprotein E (APOE) is the primary genetic risk factor for the sporadic form of Alzheimer’s disease (AD). While researchers have extensively characterized the impact that APOE ε4 (APOE4) has on the susceptibility of AD, far fewer studies have investigated the pheno...

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Detalles Bibliográficos
Autores principales: Emrani, Sheina, Arain, Hirra A., DeMarshall, Cassandra, Nuriel, Tal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643479/
https://www.ncbi.nlm.nih.gov/pubmed/33148345
http://dx.doi.org/10.1186/s13195-020-00712-4