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Gender-specific aspects of epidemiology, molecular genetics and outcome: lung cancer
Lung cancer remains the leading cause of cancer-related deaths worldwide in women and men. In incidence, lung cancer ranks second, surpassed by breast cancer in women and prostate cancer in men. However, the historical differences in mortality and incidence rate between both sexes have changed in th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643520/ https://www.ncbi.nlm.nih.gov/pubmed/33148544 http://dx.doi.org/10.1136/esmoopen-2020-000796 |
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author | Mederos, Nuria Friedlaender, Alex Peters, Solange Addeo, Alfredo |
author_facet | Mederos, Nuria Friedlaender, Alex Peters, Solange Addeo, Alfredo |
author_sort | Mederos, Nuria |
collection | PubMed |
description | Lung cancer remains the leading cause of cancer-related deaths worldwide in women and men. In incidence, lung cancer ranks second, surpassed by breast cancer in women and prostate cancer in men. However, the historical differences in mortality and incidence rate between both sexes have changed in the last years. In the last decades, we have also witnessed an increased number of lung cancer in female never-smokers. These disparities have grown our interest in studying the impact of the gender and sex in the presentation of lung cancer. The aetiology is yet to be fully elucidated, but the data are clear so far: there is a growing divide between lung cancer presentation in women and men that will change our management and study of lung cancer. This article aims to review the sex and gender differences in lung cancer. |
format | Online Article Text |
id | pubmed-7643520 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-76435202020-11-12 Gender-specific aspects of epidemiology, molecular genetics and outcome: lung cancer Mederos, Nuria Friedlaender, Alex Peters, Solange Addeo, Alfredo ESMO Open Review Lung cancer remains the leading cause of cancer-related deaths worldwide in women and men. In incidence, lung cancer ranks second, surpassed by breast cancer in women and prostate cancer in men. However, the historical differences in mortality and incidence rate between both sexes have changed in the last years. In the last decades, we have also witnessed an increased number of lung cancer in female never-smokers. These disparities have grown our interest in studying the impact of the gender and sex in the presentation of lung cancer. The aetiology is yet to be fully elucidated, but the data are clear so far: there is a growing divide between lung cancer presentation in women and men that will change our management and study of lung cancer. This article aims to review the sex and gender differences in lung cancer. BMJ Publishing Group 2020-11-03 /pmc/articles/PMC7643520/ /pubmed/33148544 http://dx.doi.org/10.1136/esmoopen-2020-000796 Text en © Author (s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. Published by BMJ on behalf of the European Society for Medical Oncology. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, any changes made are indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Review Mederos, Nuria Friedlaender, Alex Peters, Solange Addeo, Alfredo Gender-specific aspects of epidemiology, molecular genetics and outcome: lung cancer |
title | Gender-specific aspects of epidemiology, molecular genetics and outcome: lung cancer |
title_full | Gender-specific aspects of epidemiology, molecular genetics and outcome: lung cancer |
title_fullStr | Gender-specific aspects of epidemiology, molecular genetics and outcome: lung cancer |
title_full_unstemmed | Gender-specific aspects of epidemiology, molecular genetics and outcome: lung cancer |
title_short | Gender-specific aspects of epidemiology, molecular genetics and outcome: lung cancer |
title_sort | gender-specific aspects of epidemiology, molecular genetics and outcome: lung cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643520/ https://www.ncbi.nlm.nih.gov/pubmed/33148544 http://dx.doi.org/10.1136/esmoopen-2020-000796 |
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