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Regional microglial activation in the substantia nigra is linked with fatigue in MS

OBJECTIVE: The goal of our study is to assess the role of microglial activation in MS-associated fatigue (MSAF) using [F-18]PBR06-PET. METHODS: Fatigue severity was measured using the Modified Fatigue Impact Scale (MFIS) in 12 subjects with MS (7 relapsing-remitting and 5 secondary progressive) and...

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Detalles Bibliográficos
Autores principales:	Singhal, Tarun, Cicero, Steven, Pan, Hong, Carter, Kelsey, Dubey, Shipra, Chu, Renxin, Glanz, Bonnie, Hurwitz, Shelley, Tauhid, Shahamat, Park, Mi-Ae, Kijewski, Marie, Stern, Emily, Bakshi, Rohit, Silbersweig, David, Weiner, Howard L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643614/ https://www.ncbi.nlm.nih.gov/pubmed/32769103 http://dx.doi.org/10.1212/NXI.0000000000000854

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