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Postmortem CT lung findings in decedents with Covid-19: A review of 14 decedents and potential triage implications

OBJECTIVE: Computed tomography has significant utility as a diagnostic tool for coronavirus disease 2019 (COVID-19) in the clinical setting. COVID-19 deaths are sometimes examined by forensic pathologists, often in the setting of an unknown diagnosis. We assessed the utility of postmortem computed t...

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Detalles Bibliográficos
Autores principales: Helmrich, Emily, Decker, Lauren, Adolphi, Natalie, Makino, Yohsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643627/
http://dx.doi.org/10.1016/j.fri.2020.200419
Descripción
Sumario:OBJECTIVE: Computed tomography has significant utility as a diagnostic tool for coronavirus disease 2019 (COVID-19) in the clinical setting. COVID-19 deaths are sometimes examined by forensic pathologists, often in the setting of an unknown diagnosis. We assessed the utility of postmortem computed tomography (PMCT) for use as a triage tool for these autopsy examinations. MATERIALS AND METHODS: We reviewed PMCT findings in 14 and histopathology in 11 decedents who were positive for COVID-19. RESULTS: The predominant imaging findings were bilateral mixed densities, in either a diffuse or peripheral distribution, with traction bronchiectasis, and/or crazy paving. In particular, traction bronchiectasis, ill-defined rounded consolidations, and reverse halo sign are useful when distinguishing from other postmortem changes. CONCLUSION: We conclude that triage with a PMCT may aid the forensic pathologist in diagnosing possible COVID-19 infection prior to autopsy examination.