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Postmortem CT lung findings in decedents with Covid-19: A review of 14 decedents and potential triage implications
OBJECTIVE: Computed tomography has significant utility as a diagnostic tool for coronavirus disease 2019 (COVID-19) in the clinical setting. COVID-19 deaths are sometimes examined by forensic pathologists, often in the setting of an unknown diagnosis. We assessed the utility of postmortem computed t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643627/ http://dx.doi.org/10.1016/j.fri.2020.200419 |
_version_ | 1783606314561175552 |
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author | Helmrich, Emily Decker, Lauren Adolphi, Natalie Makino, Yohsuke |
author_facet | Helmrich, Emily Decker, Lauren Adolphi, Natalie Makino, Yohsuke |
author_sort | Helmrich, Emily |
collection | PubMed |
description | OBJECTIVE: Computed tomography has significant utility as a diagnostic tool for coronavirus disease 2019 (COVID-19) in the clinical setting. COVID-19 deaths are sometimes examined by forensic pathologists, often in the setting of an unknown diagnosis. We assessed the utility of postmortem computed tomography (PMCT) for use as a triage tool for these autopsy examinations. MATERIALS AND METHODS: We reviewed PMCT findings in 14 and histopathology in 11 decedents who were positive for COVID-19. RESULTS: The predominant imaging findings were bilateral mixed densities, in either a diffuse or peripheral distribution, with traction bronchiectasis, and/or crazy paving. In particular, traction bronchiectasis, ill-defined rounded consolidations, and reverse halo sign are useful when distinguishing from other postmortem changes. CONCLUSION: We conclude that triage with a PMCT may aid the forensic pathologist in diagnosing possible COVID-19 infection prior to autopsy examination. |
format | Online Article Text |
id | pubmed-7643627 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76436272020-11-06 Postmortem CT lung findings in decedents with Covid-19: A review of 14 decedents and potential triage implications Helmrich, Emily Decker, Lauren Adolphi, Natalie Makino, Yohsuke Forensic Imaging Article OBJECTIVE: Computed tomography has significant utility as a diagnostic tool for coronavirus disease 2019 (COVID-19) in the clinical setting. COVID-19 deaths are sometimes examined by forensic pathologists, often in the setting of an unknown diagnosis. We assessed the utility of postmortem computed tomography (PMCT) for use as a triage tool for these autopsy examinations. MATERIALS AND METHODS: We reviewed PMCT findings in 14 and histopathology in 11 decedents who were positive for COVID-19. RESULTS: The predominant imaging findings were bilateral mixed densities, in either a diffuse or peripheral distribution, with traction bronchiectasis, and/or crazy paving. In particular, traction bronchiectasis, ill-defined rounded consolidations, and reverse halo sign are useful when distinguishing from other postmortem changes. CONCLUSION: We conclude that triage with a PMCT may aid the forensic pathologist in diagnosing possible COVID-19 infection prior to autopsy examination. Elsevier Ltd. 2020-12 2020-11-05 /pmc/articles/PMC7643627/ http://dx.doi.org/10.1016/j.fri.2020.200419 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Helmrich, Emily Decker, Lauren Adolphi, Natalie Makino, Yohsuke Postmortem CT lung findings in decedents with Covid-19: A review of 14 decedents and potential triage implications |
title | Postmortem CT lung findings in decedents with Covid-19: A review of 14 decedents and potential triage implications |
title_full | Postmortem CT lung findings in decedents with Covid-19: A review of 14 decedents and potential triage implications |
title_fullStr | Postmortem CT lung findings in decedents with Covid-19: A review of 14 decedents and potential triage implications |
title_full_unstemmed | Postmortem CT lung findings in decedents with Covid-19: A review of 14 decedents and potential triage implications |
title_short | Postmortem CT lung findings in decedents with Covid-19: A review of 14 decedents and potential triage implications |
title_sort | postmortem ct lung findings in decedents with covid-19: a review of 14 decedents and potential triage implications |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643627/ http://dx.doi.org/10.1016/j.fri.2020.200419 |
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