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Transmission of NS5A-Inhibitor Resistance-Associated Substitutions Among Men Who Have Sex With Men Recently Infected with Hepatitis C Virus Genotype 1a
The transmission of direct-acting antiviral resistance-associated substitutions (RAS) could hamper hepatitis C virus (HCV) cure rates and elimination efforts. A phylogenetic analysis of 87 men who have sex with men recently infected with HCV genotype 1a placed one-third (28/87) in a large cluster, i...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643739/ https://www.ncbi.nlm.nih.gov/pubmed/32055843 http://dx.doi.org/10.1093/cid/ciaa145 |
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| author | Popping, Stephanie Verwijs, Rosanne Cuypers, Lize Claassen, Mark A van den Berk, Guido E De Weggheleire, Anja Arends, Joop E Boerekamps, Anne Molenkamp, Richard Koopmans, Marion P Verbon, Annelies Boucher, Charles A B Rijnders, Bart J van de Vijver, David A M C |
| author_facet | Popping, Stephanie Verwijs, Rosanne Cuypers, Lize Claassen, Mark A van den Berk, Guido E De Weggheleire, Anja Arends, Joop E Boerekamps, Anne Molenkamp, Richard Koopmans, Marion P Verbon, Annelies Boucher, Charles A B Rijnders, Bart J van de Vijver, David A M C |
| author_sort | Popping, Stephanie |
| collection | PubMed |
| description | The transmission of direct-acting antiviral resistance-associated substitutions (RAS) could hamper hepatitis C virus (HCV) cure rates and elimination efforts. A phylogenetic analysis of 87 men who have sex with men recently infected with HCV genotype 1a placed one-third (28/87) in a large cluster, in which 96% harbored NS5A M28V RAS. |
| format | Online Article Text |
| id | pubmed-7643739 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-76437392020-11-12 Transmission of NS5A-Inhibitor Resistance-Associated Substitutions Among Men Who Have Sex With Men Recently Infected with Hepatitis C Virus Genotype 1a Popping, Stephanie Verwijs, Rosanne Cuypers, Lize Claassen, Mark A van den Berk, Guido E De Weggheleire, Anja Arends, Joop E Boerekamps, Anne Molenkamp, Richard Koopmans, Marion P Verbon, Annelies Boucher, Charles A B Rijnders, Bart J van de Vijver, David A M C Clin Infect Dis Online Only Articles The transmission of direct-acting antiviral resistance-associated substitutions (RAS) could hamper hepatitis C virus (HCV) cure rates and elimination efforts. A phylogenetic analysis of 87 men who have sex with men recently infected with HCV genotype 1a placed one-third (28/87) in a large cluster, in which 96% harbored NS5A M28V RAS. Oxford University Press 2020-02-14 /pmc/articles/PMC7643739/ /pubmed/32055843 http://dx.doi.org/10.1093/cid/ciaa145 Text en © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
| spellingShingle | Online Only Articles Popping, Stephanie Verwijs, Rosanne Cuypers, Lize Claassen, Mark A van den Berk, Guido E De Weggheleire, Anja Arends, Joop E Boerekamps, Anne Molenkamp, Richard Koopmans, Marion P Verbon, Annelies Boucher, Charles A B Rijnders, Bart J van de Vijver, David A M C Transmission of NS5A-Inhibitor Resistance-Associated Substitutions Among Men Who Have Sex With Men Recently Infected with Hepatitis C Virus Genotype 1a |
| title | Transmission of NS5A-Inhibitor Resistance-Associated Substitutions Among Men Who Have Sex With Men Recently Infected with Hepatitis C Virus Genotype 1a |
| title_full | Transmission of NS5A-Inhibitor Resistance-Associated Substitutions Among Men Who Have Sex With Men Recently Infected with Hepatitis C Virus Genotype 1a |
| title_fullStr | Transmission of NS5A-Inhibitor Resistance-Associated Substitutions Among Men Who Have Sex With Men Recently Infected with Hepatitis C Virus Genotype 1a |
| title_full_unstemmed | Transmission of NS5A-Inhibitor Resistance-Associated Substitutions Among Men Who Have Sex With Men Recently Infected with Hepatitis C Virus Genotype 1a |
| title_short | Transmission of NS5A-Inhibitor Resistance-Associated Substitutions Among Men Who Have Sex With Men Recently Infected with Hepatitis C Virus Genotype 1a |
| title_sort | transmission of ns5a-inhibitor resistance-associated substitutions among men who have sex with men recently infected with hepatitis c virus genotype 1a |
| topic | Online Only Articles |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643739/ https://www.ncbi.nlm.nih.gov/pubmed/32055843 http://dx.doi.org/10.1093/cid/ciaa145 |
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