The Diagnostic Pitfalls of Mucormycosis

BACKGROUND: Invasive mucormycosis is a very aggressive fungal disease among immunocompromised pediatric patients caused by saprophytic fungi that belong to the order of the Mucorales. CASE REPORT: We describe a case of of Lichtheimia corymbifera infection in a 15-year-old child with B-cell-Non-Hodgk...

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Autores principales: Mauro, Margherita, Lo Cascio, Giuliana, Balter, Rita, Zaccaron, Ada, Bonetti, Elisa, Vitale, Virginia, Chinello, Matteo, De Bortoli, Massimiliano, Brazzarola, Paolo, Bruno, Costanza, Cesaro, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643780/
https://www.ncbi.nlm.nih.gov/pubmed/33194153
http://dx.doi.org/10.4084/MJHID.2020.079
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author Mauro, Margherita
Lo Cascio, Giuliana
Balter, Rita
Zaccaron, Ada
Bonetti, Elisa
Vitale, Virginia
Chinello, Matteo
De Bortoli, Massimiliano
Brazzarola, Paolo
Bruno, Costanza
Cesaro, Simone
author_facet Mauro, Margherita
Lo Cascio, Giuliana
Balter, Rita
Zaccaron, Ada
Bonetti, Elisa
Vitale, Virginia
Chinello, Matteo
De Bortoli, Massimiliano
Brazzarola, Paolo
Bruno, Costanza
Cesaro, Simone
author_sort Mauro, Margherita
collection PubMed
description BACKGROUND: Invasive mucormycosis is a very aggressive fungal disease among immunocompromised pediatric patients caused by saprophytic fungi that belong to the order of the Mucorales. CASE REPORT: We describe a case of of Lichtheimia corymbifera infection in a 15-year-old child with B-cell-Non-Hodgkin Lymphoma (B-NHL) involving lung, kidney and thyroid that initially was diagnosed as probable aspergillosis delaying the effective therapy for mucormycosis. CONCLUSIONS: This case showed that also the intensive chemotherapy for B-NHL may represent a risk factor for mucormycosis infection. Liposomal amphotericin B and surgery remain the key tools for the successful treatment of this aggressive disease.
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spelling pubmed-76437802020-11-13 The Diagnostic Pitfalls of Mucormycosis Mauro, Margherita Lo Cascio, Giuliana Balter, Rita Zaccaron, Ada Bonetti, Elisa Vitale, Virginia Chinello, Matteo De Bortoli, Massimiliano Brazzarola, Paolo Bruno, Costanza Cesaro, Simone Mediterr J Hematol Infect Dis Case Report BACKGROUND: Invasive mucormycosis is a very aggressive fungal disease among immunocompromised pediatric patients caused by saprophytic fungi that belong to the order of the Mucorales. CASE REPORT: We describe a case of of Lichtheimia corymbifera infection in a 15-year-old child with B-cell-Non-Hodgkin Lymphoma (B-NHL) involving lung, kidney and thyroid that initially was diagnosed as probable aspergillosis delaying the effective therapy for mucormycosis. CONCLUSIONS: This case showed that also the intensive chemotherapy for B-NHL may represent a risk factor for mucormycosis infection. Liposomal amphotericin B and surgery remain the key tools for the successful treatment of this aggressive disease. Università Cattolica del Sacro Cuore 2020-11-01 /pmc/articles/PMC7643780/ /pubmed/33194153 http://dx.doi.org/10.4084/MJHID.2020.079 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mauro, Margherita
Lo Cascio, Giuliana
Balter, Rita
Zaccaron, Ada
Bonetti, Elisa
Vitale, Virginia
Chinello, Matteo
De Bortoli, Massimiliano
Brazzarola, Paolo
Bruno, Costanza
Cesaro, Simone
The Diagnostic Pitfalls of Mucormycosis
title The Diagnostic Pitfalls of Mucormycosis
title_full The Diagnostic Pitfalls of Mucormycosis
title_fullStr The Diagnostic Pitfalls of Mucormycosis
title_full_unstemmed The Diagnostic Pitfalls of Mucormycosis
title_short The Diagnostic Pitfalls of Mucormycosis
title_sort diagnostic pitfalls of mucormycosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643780/
https://www.ncbi.nlm.nih.gov/pubmed/33194153
http://dx.doi.org/10.4084/MJHID.2020.079
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