A phase II study of the insulin-like growth factor type I receptor inhibitor IMC-A12 in patients with metastatic uveal melanoma

Uveal melanoma is a rare and aggressive malignancy and up to half of all patients will develop metastatic disease despite the effective treatment of the primary tumor. Insulin-like growth factors I/II play a fundamental role in the cell migration, proliferation, and apoptosis. IMC-A12, a mAb specifi...

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Detalles Bibliográficos
Autores principales: Mattei, Jane, Ballhausen, Alexej, Bassett, Roland, Shephard, Michael, Chattopadhyay, Chandrani, Hudgens, Courtney, Tetzlaff, Michael, Woodman, Scott, Sato, Takami, Patel, Sapna P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Original Articles: Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643799/
https://www.ncbi.nlm.nih.gov/pubmed/32976223
http://dx.doi.org/10.1097/CMR.0000000000000694

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